BioSyn-Bisabolol

BioSyn-Bisabolol

INCI name: Bisabolol
NATURAL SOOTHING INGREDIENT
Personal care · Anti-Allergy & Soothing
Synthetic Biology

BioSyn-Bisabolol contains the active (-)-α-bisabolol, produced via sustainable fermentation. It received the 2023 in-cosmetics Asia Bronze Award (Sustainable, Conscious Beauty), confirming industry recognition.


With purity ≥95% and 100% bio-based carbon content, it ensures high biological activity and eco-friendly sourcing.In anti-inflammatory tests, it inhibited IL-6, TNF-α, and NO by 76%, 77%, and 80%, respectively, demonstrating strong soothing efficacy.It is suitable for sensitive skin, baby care, and after-sun products, compatible with common cosmetic formulation

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BioSyn-Bisabolol

ADVANTAGES

1.Higher Purity (≥99%): The content of active (-)-α-bisabolol reaches 99% or higher and there is no other isomer. This high purity ensures superior biological activity and batch-to-batch consistency.


2.Multi-Action Efficacy: In lab tests, it inhibits key inflammatory markers (IL-6, TNF-α) by over 76% and demonstrates antimicrobial activity. This validates its use for soothing sensitive skin and enhancing product preservation.


3.Sustainable & Stable Supply: Produced via large-scale fermentation, this method guarantees a consistent, scalable supply independent of seasonal plant harvesting, supporting long-term production planning.


4.Eco-Friendly Process: The fermentation process utilizes 100% bio-based carbon, resulting in a carbon footprint reduction exceeding 90% compared to traditional synthetic or extraction methods. This aligns with stringent green chemistry standards.

EFFICACIES

Anti-inflammatory & Soothing: In lab tests, it inhibits key inflammatory markers IL-6, TNF-α, and NO by 76%, 77%, and 80%, respectively. This demonstrates potent reduction of skin sensitivity and irritation.


Antioxidant: Significantly suppresses reactive oxygen species (ROS) in PMN respiratory burst models. This activity protects skin from oxidative stress, slowing the aging process.


Barrier Repair & Wound Healing: Enhances skin recovery by promoting transdermal absorption while reducing moisture loss. This supports healing in minor skin damage or inflammation.


Whitening: Reduces intracellular cAMP levels and CREB phosphorylation, inhibiting α-MSH-induced melanin production. This mechanism leads to visibly brighter skin tone.

FAQ

Q1: What are the main effects of BioSyn-Bisabolol?


A1: 

Anti-inflammatory and soothing:BioSyn-Bisabolol rapidly relieves redness and stinging of the skin by inhibiting the release of inflammatory factors (e.g. COX-2, TNF-α, IL-6), especially for sensitive skin and rosacea.

Barrier Repair: BioSyn-Bisabolol promotes keratinocyte proliferation, accelerates repair of damaged skin, reduces transdermal water loss (TEWL), and enhances skin's ability to lock in water.

Aids in anti-acne whitening:BioSyn-Bisabolol can inhibit the activity of Propionibacterium acnes to help improve acne problems; it can also inhibit tyrosinase to achieve a significant brightening effect.


Q2: Which skin types are suitable to use products containing BioSyn-Bisabolol ?


A2: People with sensitive and damaged skin can choose to use BioSyn-Bisabolol, its low-irritation formula can soothe acid brushing, burning sensation after sun exposure, and repair the barrier fragility problems.  Infants and people with acne-prone skin can also choose to use BioSyn-Bisabolol,  whose antibacterial properties assist in combating acne and is safe enough to be widely used in infant skincare products.

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